NIBRT Database Collection

the beauty of a glycan is not the sugars that go into it, but the way those sugars are put together

Welcome to the GlycoBase 3.2 suite of databases

Access to the Pub-Collections within GlycoBase 3.2 is free and does not require login.

All commercial users wishing to access Pro-Collections are required to sign a license agreement with NIBRT. Please request additional information about licensing and fees here.
Academic users have 30 days free access to the Pro-Collections within GlycoBase 3.2 once approved. Please request additional information here.

To have more information about GlycoBase 3.2, check out the FAQ page!
If you have any requests, please contact us at here.

If you are a new user wishing to access the Pro collections, please, complete the registration form here.

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NIBRT provides a range of contract glycan assessment analytical services to a diverse client base. These services are based on NIBRT's proprietary high-throughput HPLC based glycan analysis technology. Some of the key features of NIBRT's analytical services are:

• High degree of sensitivity (LOD 2 femtomoles of sugar; 1% of glycan pool).
• High-throughput method based on 96 well format.
• Orthogonal verification using Mass Spec.
• Cost effective and efficient management of client's requirements.

For further information on these services please contact us at info@nibrt.ie.

Recent publications by the group can be found here.

• High-throughput glycome analysis is set to join high-throughput genomics. Rudd PM, Rudan I, Wright AF. J Proteome Res. 2009 Mar;8(3):1105.
• Variability, heritability and environmental determinants of human plasma N-glycome. Knezevic A., et al., J Proteome Res. 2009 Feb;8(2):694-701.
• The Impact of Glycosylation on the Biological Function and Structure of Human Immunoglobulins. Arnold, J.N., et al. (2007) Annu Rev Immunol, 25 21-50
• Glycobiology and Medicine. Rudd, P.M. and R.A. Dwek (2006) The Biochemist, 28 3, 18-21
• Glycobiology - discovery, diagnostics and drugs, in Glycobiology, C. Sansom and O. Markman, Editors. 2007, Scion publishing Limited. p. 8 - 11.
• A spoonful of sugar. Nature Vol 457 29 January 2009, Technology Feature Glycobiology.
• Commercial interest grows in glycan analysis. Sheridan, C. (2007) Nat Biotechnol, 25 2, 145-6
• Biologic Drugs - Understanding their Complexity Chemical and Engineering News
• Advances in the Analysis of Glycans for the Characterization of Biopharmaceuticals Genetic Engineering and Biotech News
• Separation-based Glycoprofiling Approaches using Fluorescent Labels. P.J. Domann, A.C. Pardos-Pardos, D.L. Fernandes, D.I. Spencer, C.M. Radcliffe, L. Royle, R.A. Dwek, P.M. Rudd (2007) Proteomics, 7 Suppl 1, 70-76.
• HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software Royle, L., et al. (2008) Anal Biochem, 376 1, 1-12

Under the EU FP7 framework, GlycoBioM project sponsors the development of GlycoBase. The overall aim of the consortium is to develop the next generation diagnostic tool kit for the screening and analysis of carbohydrate biomarkers.

The UniCarb-DB project was initiated in 2009 as a continuation of the EUROCarbDB with the initial ambition to provide a platform for structural and analytical data storage and retrieval associated with glycomic experiments.

Minimum Information Required for A GLycomics Experiment

UniCarbKB is an initiative that aims to promote the creation of an online information storage and search platform for glycomics and glycobiology research. The knowledgebase will offer a freely accessible and information-rich resource supported by querying interfaces, annotation technologies and the adoption of common standards to integrate structural, experimental and functional data.

The GlycoSuite database (GlycoSuiteDB) is an annotated and curated relational database of glycan structures and is a product of Tyrian Diagnostics Ltd (formerly Proteome Systems Ltd). Currently, the database contains most published O-linked glycans, and N-linked glycans in the literature from the years 1990-2005.

a tool for calculating composition of glycans from MS data

a database of pathogen-glycan interactions

an environment for 3-D glycan structures

a web resource providing algorithmic and data mining tools

MonosaccharideDB is a comprehensive resource of monosaccharide data and information.

A portal for querying across the digital world of carbohydrate sequences